Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM4650'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM4650 (Anilinoquinazoline deriv. 33 | N-(2-Fluoro-5-hydro...) Show SMILES COCC(=O)Nc1cc2ncnc(Nc3cc(O)c(C)cc3F)c2cc1OC Show InChI InChI=1S/C19H19FN4O4/c1-10-4-12(20)14(7-16(10)25)24-19-11-5-17(28-3)15(23-18(26)8-27-2)6-13(11)21-9-22-19/h4-7,9,25H,8H2,1-3H3,(H,23,26)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	25
AstraZeneca					Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit FGFR-1 TK activity. The compounds were incubated with enzyme 20 min at room ...				J Med Chem 42: 5369-89 (1999) Article DOI: 10.1021/jm990345w BindingDB Entry DOI: 10.7270/Q2F47MBM
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