Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4812 ((3Z)-3-({3,5-dimethyl-4-[3-(4-methylpiperazin-1-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 46: 1116-9 (2003) Article DOI: 10.1021/jm0204183 BindingDB Entry DOI: 10.7270/Q2D50K5B | |||||||||||
More data for this Ligand-Target Pair |