BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM4837'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM4837
PNG
(1-[2-amino-6-(2,4,6-trimethylphenyl)pyrido[2,3-d]p...)
Show SMILES Cc1cc(C)c(c(C)c1)-c1cc2cnc(N)nc2nc1NC(=O)NC(C)(C)C |(6.24,5.02,;4.91,4.25,;3.58,5.02,;2.24,4.25,;.91,5.02,;2.24,2.71,;3.58,1.94,;3.51,.4,;4.82,2.53,;.91,1.94,;-.42,2.71,;-1.76,1.94,;-3.09,2.71,;-4.43,1.94,;-4.43,.4,;-5.76,-.37,;-3.09,-.37,;-1.76,.4,;-.42,-.37,;.91,.4,;2.4,-0,;2.8,-1.49,;1.71,-2.58,;4.28,-1.89,;5.37,-.8,;6.86,-1.2,;4.97,.69,;6.46,.29,)|
Show InChI InChI=1S/C21H26N6O/c1-11-7-12(2)16(13(3)8-11)15-9-14-10-23-19(22)25-17(14)24-18(15)26-20(28)27-21(4,5)6/h7-10H,1-6H3,(H4,22,23,24,25,26,27,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 270n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labeled ATP to the poly (E: Y) subs...


Bioorg Med Chem Lett 7: 2415-20 (1997)


Article DOI: 10.1074/jbc.M606873200
BindingDB Entry DOI: 10.7270/Q28C9TF2
More data for this
Ligand-Target Pair