BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM4918'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM4918
PNG
(3-(2-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3...)
Show SMILES COc1ccc2\C(=C\c3[nH]c4CCCCc4c3CCC(O)=O)C(=O)Nc2c1
Show InChI InChI=1S/C21H22N2O4/c1-27-12-6-7-15-16(21(26)23-18(15)10-12)11-19-14(8-9-20(24)25)13-4-2-3-5-17(13)22-19/h6-7,10-11,22H,2-5,8-9H2,1H3,(H,23,26)(H,24,25)/b16-11-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.08E+3n/an/an/an/an/an/a



SUGEN, Inc.



Assay Description
The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...


J Med Chem 43: 2655-63 (2000)


Article DOI: 10.1021/jm9906116
BindingDB Entry DOI: 10.7270/Q2W66J0N
More data for this
Ligand-Target Pair