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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM50168404'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50168404
PNG
(2,4-Difluoro-5-(5-isopropyl-6-[1,3,4]oxadiazol-2-y...)
Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnco4)c(C(C)C)c23)c(F)cc1F
Show InChI InChI=1S/C19H17F2N7O3/c1-9(2)15-11(19-26-23-8-31-19)6-28-16(15)17(22-7-24-28)25-14-4-10(18(29)27-30-3)12(20)5-13(14)21/h4-9H,1-3H3,(H,27,29)(H,22,24,25)
PDB
MMDB

NCI pathway
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PC cid
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Similars

Article
PubMed
n/an/a 160n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human fibroblast growth factor receptor 1


J Med Chem 48: 3991-4008 (2005)


Article DOI: 10.1021/jm0501275
BindingDB Entry DOI: 10.7270/Q2KP81QN
More data for this
Ligand-Target Pair