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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM50189792'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50189792
PNG
(CHEMBL3828317)
Show SMILES C(Oc1ccc2[nH]nc(-c3nc4cc(ccc4[nH]3)N3CCCCC3)c2c1)c1ccccn1
Show InChI InChI=1S/C25H24N6O/c1-4-12-31(13-5-1)18-7-9-22-23(14-18)28-25(27-22)24-20-15-19(8-10-21(20)29-30-24)32-16-17-6-2-3-11-26-17/h2-3,6-11,14-15H,1,4-5,12-13,16H2,(H,27,28)(H,29,30)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.10n/an/an/an/an/an/a



East China University of Science& Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human FGFR1 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA


J Med Chem 59: 6690-708 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00056
BindingDB Entry DOI: 10.7270/Q2474CT3
More data for this
Ligand-Target Pair