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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM50260200'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50260200
PNG
(CHEMBL4064676)
Show SMILES CNc1ncc2CN(C(=O)N([C@@H]3CCCN(C3)C(=O)\C=C\CN(C)C)c2n1)c1c(Cl)c(OC)cc(OC)c1Cl |r|
Show InChI InChI=1S/C26H33Cl2N7O4/c1-29-25-30-13-16-14-34(23-21(27)18(38-4)12-19(39-5)22(23)28)26(37)35(24(16)31-25)17-8-6-11-33(15-17)20(36)9-7-10-32(2)3/h7,9,12-13,17H,6,8,10-11,14-15H2,1-5H3,(H,29,30,31)/b9-7+/t17-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.5n/an/an/an/an/an/a



Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged FGFR1 cytoplasmic domain (308 to 731 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by ...


Eur J Med Chem 135: 531-543 (2017)


Article DOI: 10.1016/j.ejmech.2017.04.049
BindingDB Entry DOI: 10.7270/Q2K076QF
More data for this
Ligand-Target Pair