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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM6169'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM6169
PNG
(1,6-naphthyridine 38 | N-[3-(Benzyloxy)propyl]-N-[...)
Show SMILES COc1cc(OC)cc(c1)-c1cc2cnc(cc2nc1NC(=O)NC(C)(C)C)N(CCCOCc1ccccc1)C(C)=O
Show InChI InChI=1S/C33H39N5O5/c1-22(39)38(13-10-14-43-21-23-11-8-7-9-12-23)30-19-29-25(20-34-30)17-28(24-15-26(41-5)18-27(16-24)42-6)31(35-29)36-32(40)37-33(2,3)4/h7-9,11-12,15-20H,10,13-14,21H2,1-6H3,(H2,35,36,37,40)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...


J Med Chem 48: 4628-53 (2005)


Article DOI: 10.1021/jm0500931
BindingDB Entry DOI: 10.7270/Q2DV1H3W
More data for this
Ligand-Target Pair