Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM339840'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM339840 (US9757364, Compound 37 | US9757364, Compound 41) Show SMILES COc1cc(OC)cc(c1)N(CC1CCC(=O)N1)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C25H26N6O3/c1-30-14-17(13-27-30)16-8-23-22(26-12-16)5-6-24(29-23)31(15-18-4-7-25(32)28-18)19-9-20(33-2)11-21(10-19)34-3/h5-6,8-14,18H,4,7,15H2,1-3H3,(H,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.86	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM339840 (US9757364, Compound 37 | US9757364, Compound 41) Show SMILES COc1cc(OC)cc(c1)N(CC1CCC(=O)N1)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C25H26N6O3/c1-30-14-17(13-27-30)16-8-23-22(26-12-16)5-6-24(29-23)31(15-18-4-7-25(32)28-18)19-9-20(33-2)11-21(10-19)34-3/h5-6,8-14,18H,4,7,15H2,1-3H3,(H,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.88	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
					More data for this Ligand-Target Pair