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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM50260188'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM50260188
PNG
(CHEMBL4069509)
Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc(NC(C)C)nc3N(C3CCN(CC3)C(=O)\C=C\CN(C)C)C2=O)c1Cl
Show InChI InChI=1S/C28H37Cl2N7O4/c1-17(2)32-27-31-15-18-16-36(25-23(29)20(40-5)14-21(41-6)24(25)30)28(39)37(26(18)33-27)19-9-12-35(13-10-19)22(38)8-7-11-34(3)4/h7-8,14-15,17,19H,9-13,16H2,1-6H3,(H,31,32,33)/b8-7+
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MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a



Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cytoplasmic His-tagged FGFR2 (403 to 822 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by FRET-ba...


Eur J Med Chem 135: 531-543 (2017)


Article DOI: 10.1016/j.ejmech.2017.04.049
BindingDB Entry DOI: 10.7270/Q2K076QF
More data for this
Ligand-Target Pair