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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM50260193'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM50260193
PNG
(CHEMBL4092354)
Show SMILES CNc1ncc2CN(C(=O)N(C3CCN(CC3)C(=O)\C=C\CN(C)C)c2n1)c1c(Cl)c(OC)cc(OC)c1Cl
Show InChI InChI=1S/C26H33Cl2N7O4/c1-29-25-30-14-16-15-34(23-21(27)18(38-4)13-19(39-5)22(23)28)26(37)35(24(16)31-25)17-8-11-33(12-9-17)20(36)7-6-10-32(2)3/h6-7,13-14,17H,8-12,15H2,1-5H3,(H,29,30,31)/b7-6+
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MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.60n/an/an/an/an/an/a



Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cytoplasmic His-tagged FGFR2 (403 to 822 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by FRET-ba...


Eur J Med Chem 135: 531-543 (2017)


Article DOI: 10.1016/j.ejmech.2017.04.049
BindingDB Entry DOI: 10.7270/Q2K076QF
More data for this
Ligand-Target Pair