Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM128629'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM128629 (US8796244, 218) Show SMILES CNc1cc(nc(SC)n1)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C22H20F3N7OS/c1-26-18-10-16(30-21(31-18)34-2)13-6-7-32-17(11-27-19(32)9-13)14-4-3-5-15(8-14)29-20(33)28-12-22(23,24)25/h3-11H,12H2,1-2H3,(H,26,30,31)(H2,28,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	8.0	25
Astex Therapeutics Ltd US Patent					Assay Description Enzymes (from Upstate) were prepared at 2× final concentration in 1× kinase assay buffer (Table 1). Enzymes were then incubated with test compounds, ...				US Patent US8796244 (2014) BindingDB Entry DOI: 10.7270/Q20C4TFP
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