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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1' and Ligand = 'BDBM166937'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Flap endonuclease 1


(Homo sapiens (Human))
BDBM166937
PNG
(US9073876, 23 | US9732093, Compound 23)
Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(OCc2ccc(CC(O)=O)cc2)c1F
Show InChI InChI=1S/C23H22FN3O3/c24-22-18(19-11-27-20(25)12-26-19)9-8-17(16-2-1-3-16)23(22)30-13-15-6-4-14(5-7-15)10-21(28)29/h4-9,11-12,16H,1-3,10,13H2,(H2,25,27)(H,28,29)
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KEGG
PC cid
PC sid
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US Patent
2n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent




US Patent US9732093 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MCX
More data for this
Ligand-Target Pair
Flap endonuclease 1


(Homo sapiens (Human))
BDBM166937
PNG
(US9073876, 23 | US9732093, Compound 23)
Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(OCc2ccc(CC(O)=O)cc2)c1F
Show InChI InChI=1S/C23H22FN3O3/c24-22-18(19-11-27-20(25)12-26-19)9-8-17(16-2-1-3-16)23(22)30-13-15-6-4-14(5-7-15)10-21(28)29/h4-9,11-12,16H,1-3,10,13H2,(H2,25,27)(H,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
US Patent
3.70n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent




US Patent US9732093 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MCX
More data for this
Ligand-Target Pair