Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1' and Ligand = 'BDBM166937'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Flap endonuclease 1 (Homo sapiens (Human))	BDBM166937 (US9073876, 23 | US9732093, Compound 23) Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(OCc2ccc(CC(O)=O)cc2)c1F Show InChI InChI=1S/C23H22FN3O3/c24-22-18(19-11-27-20(25)12-26-19)9-8-17(16-2-1-3-16)23(22)30-13-15-6-4-14(5-7-15)10-21(28)29/h4-9,11-12,16H,1-3,10,13H2,(H2,25,27)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9732093 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MCX
					More data for this Ligand-Target Pair
Flap endonuclease 1 (Homo sapiens (Human))	BDBM166937 (US9073876, 23 | US9732093, Compound 23) Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(OCc2ccc(CC(O)=O)cc2)c1F Show InChI InChI=1S/C23H22FN3O3/c24-22-18(19-11-27-20(25)12-26-19)9-8-17(16-2-1-3-16)23(22)30-13-15-6-4-14(5-7-15)10-21(28)29/h4-9,11-12,16H,1-3,10,13H2,(H2,25,27)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9732093 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MCX
					More data for this Ligand-Target Pair