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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1' and Ligand = 'BDBM167024'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Flap endonuclease 1


(Homo sapiens (Human))
BDBM167024
PNG
(US9073876, 110 | US9732093, Compound 110)
Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2ncccc2C#N)c1F
Show InChI InChI=1S/C20H16FN5O/c21-18-15(16-10-26-17(23)11-25-16)7-6-14(12-3-1-4-12)19(18)27-20-13(9-22)5-2-8-24-20/h2,5-8,10-12H,1,3-4H2,(H2,23,26)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
2.40n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent




US Patent US9732093 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MCX
More data for this
Ligand-Target Pair
Flap endonuclease 1


(Homo sapiens (Human))
BDBM167024
PNG
(US9073876, 110 | US9732093, Compound 110)
Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2ncccc2C#N)c1F
Show InChI InChI=1S/C20H16FN5O/c21-18-15(16-10-26-17(23)11-25-16)7-6-14(12-3-1-4-12)19(18)27-20-13(9-22)5-2-8-24-20/h2,5-8,10-12H,1,3-4H2,(H2,23,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.60n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent




US Patent US9732093 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MCX
More data for this
Ligand-Target Pair