Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1' and Ligand = 'BDBM167025'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Flap endonuclease 1 (Homo sapiens (Human))	BDBM167025 (US9073876, 111 | US9732093, Compound 111) Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2cccc(n2)C#N)c1F Show InChI InChI=1S/C20H16FN5O/c21-19-15(16-10-25-17(23)11-24-16)8-7-14(12-3-1-4-12)20(19)27-18-6-2-5-13(9-22)26-18/h2,5-8,10-12H,1,3-4H2,(H2,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9732093 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MCX
					More data for this Ligand-Target Pair
Flap endonuclease 1 (Homo sapiens (Human))	BDBM167025 (US9073876, 111 | US9732093, Compound 111) Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2cccc(n2)C#N)c1F Show InChI InChI=1S/C20H16FN5O/c21-19-15(16-10-25-17(23)11-24-16)8-7-14(12-3-1-4-12)20(19)27-18-6-2-5-13(9-22)26-18/h2,5-8,10-12H,1,3-4H2,(H2,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9732093 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MCX
					More data for this Ligand-Target Pair