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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1' and Ligand = 'BDBM167056'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Flap endonuclease 1


(Homo sapiens (Human))
BDBM167056
PNG
(US9073876, 142 | US9732093, Compound 142)
Show SMILES COCc1cc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)cn2)nc(N)n1
Show InChI InChI=1S/C20H21FN6O2/c1-28-10-12-7-17(27-20(23)26-12)29-19-13(11-3-2-4-11)5-6-14(18(19)21)15-8-25-16(22)9-24-15/h5-9,11H,2-4,10H2,1H3,(H2,22,25)(H2,23,26,27)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
1.70n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent




US Patent US9732093 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MCX
More data for this
Ligand-Target Pair
Flap endonuclease 1


(Homo sapiens (Human))
BDBM167056
PNG
(US9073876, 142 | US9732093, Compound 142)
Show SMILES COCc1cc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)cn2)nc(N)n1
Show InChI InChI=1S/C20H21FN6O2/c1-28-10-12-7-17(27-20(23)26-12)29-19-13(11-3-2-4-11)5-6-14(18(19)21)15-8-25-16(22)9-24-15/h5-9,11H,2-4,10H2,1H3,(H2,22,25)(H2,23,26,27)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.70n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent




US Patent US9732093 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MCX
More data for this
Ligand-Target Pair