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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1' and Ligand = 'BDBM167083'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Flap endonuclease 1


(Homo sapiens (Human))
BDBM167083
PNG
(US9073876, 168 | US9732093, Compound 168)
Show SMILES CC(C)c1cc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)nc2)nc(N)n1
Show InChI InChI=1S/C21H23FN6O/c1-11(2)16-8-17(28-21(24)27-16)29-19-15(12-4-3-5-12)7-6-14(18(19)22)13-9-25-20(23)26-10-13/h6-12H,3-5H2,1-2H3,(H2,23,25,26)(H2,24,27,28)
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PC cid
PC sid
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US Patent
2.80n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent




US Patent US9732093 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MCX
More data for this
Ligand-Target Pair
Flap endonuclease 1


(Homo sapiens (Human))
BDBM167083
PNG
(US9073876, 168 | US9732093, Compound 168)
Show SMILES CC(C)c1cc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)nc2)nc(N)n1
Show InChI InChI=1S/C21H23FN6O/c1-11(2)16-8-17(28-21(24)27-16)29-19-15(12-4-3-5-12)7-6-14(18(19)22)13-9-25-20(23)26-10-13/h6-12H,3-5H2,1-2H3,(H2,23,25,26)(H2,24,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.80n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent




US Patent US9732093 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MCX
More data for this
Ligand-Target Pair