Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1' and Ligand = 'BDBM167148'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Flap endonuclease 1 (Homo sapiens (Human))	BDBM167148 (US9073876, 230 | US9732093, Compound 230) Show SMILES Fc1c(Oc2ncccn2)c(ccc1-c1cnc2[nH]ccc2n1)C1CCC1 Show InChI InChI=1S/C20H16FN5O/c21-17-14(16-11-25-19-15(26-16)7-10-22-19)6-5-13(12-3-1-4-12)18(17)27-20-23-8-2-9-24-20/h2,5-12H,1,3-4H2,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9732093 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MCX
					More data for this Ligand-Target Pair
Flap endonuclease 1 (Homo sapiens (Human))	BDBM167148 (US9073876, 230 | US9732093, Compound 230) Show SMILES Fc1c(Oc2ncccn2)c(ccc1-c1cnc2[nH]ccc2n1)C1CCC1 Show InChI InChI=1S/C20H16FN5O/c21-17-14(16-11-25-19-15(26-16)7-10-22-19)6-5-13(12-3-1-4-12)18(17)27-20-23-8-2-9-24-20/h2,5-12H,1,3-4H2,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9732093 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MCX
					More data for this Ligand-Target Pair