new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1' and Ligand = 'BDBM167180'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Flap endonuclease 1


(Homo sapiens (Human))
BDBM167180
PNG
(US9073876, 261 | US9732093, Compound 261)
Show SMILES CC(C)CNc1nccc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)cn2)n1
Show InChI InChI=1S/C22H25FN6O/c1-13(2)10-28-22-25-9-8-19(29-22)30-21-15(14-4-3-5-14)6-7-16(20(21)23)17-11-27-18(24)12-26-17/h6-9,11-14H,3-5,10H2,1-2H3,(H2,24,27)(H,25,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.30n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent




US Patent US9732093 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MCX
More data for this
Ligand-Target Pair
Flap endonuclease 1


(Homo sapiens (Human))
BDBM167180
PNG
(US9073876, 261 | US9732093, Compound 261)
Show SMILES CC(C)CNc1nccc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)cn2)n1
Show InChI InChI=1S/C22H25FN6O/c1-13(2)10-28-22-25-9-8-19(29-22)30-21-15(14-4-3-5-14)6-7-16(20(21)23)17-11-27-18(24)12-26-17/h6-9,11-14H,3-5,10H2,1-2H3,(H2,24,27)(H,25,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.20n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent




US Patent US9732093 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MCX
More data for this
Ligand-Target Pair