Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Focal adhesion kinase 1' and Ligand = 'BDBM134190'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM134190 (US8846689, 192) Show SMILES CN1Cc2cccc(Oc3nc(Nc4ccc(cc4C)C(=O)NC4CCCN(C)C4)ncc3C(F)(F)F)c2C1=O Show InChI InChI=1S/C28H29F3N6O3/c1-16-12-17(24(38)33-19-7-5-11-36(2)15-19)9-10-21(16)34-27-32-13-20(28(29,30)31)25(35-27)40-22-8-4-6-18-14-37(3)26(39)23(18)22/h4,6,8-10,12-13,19H,5,7,11,14-15H2,1-3H3,(H,33,38)(H,32,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec...				US Patent US8846689 (2014) BindingDB Entry DOI: 10.7270/Q2BC3X7Z
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