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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Focal adhesion kinase 1' and Ligand = 'BDBM50181997'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50181997
PNG
(7-(pyridin-3-ylmethyl)-N-(3,4,5-trimethoxyphenyl)-...)
Show SMILES COc1cc(Nc2ncc3ccn(Cc4cccnc4)c3n2)cc(OC)c1OC
Show InChI InChI=1S/C21H21N5O3/c1-27-17-9-16(10-18(28-2)19(17)29-3)24-21-23-12-15-6-8-26(20(15)25-21)13-14-5-4-7-22-11-14/h4-12H,13H2,1-3H3,(H,23,24,25)
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MMDB

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n/an/a 7.90E+3n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibitory activity against FAK

Bioorg Med Chem Lett 16: 2173-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.053
BindingDB Entry DOI: 10.7270/Q2319VGX
More data for this
Ligand-Target Pair