Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Focal adhesion kinase 1' and Ligand = 'BDBM50246190'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50246190 ((R)-5-(4-(2-oxoazepan-3-ylamino)-5-(trifluoromethy...) Show SMILES FC(F)(F)c1cnc(Nc2ccc3NC(=O)Cc3c2)nc1N[C@@H]1CCCCNC1=O |r| Show InChI InChI=1S/C19H19F3N6O2/c20-19(21,22)12-9-24-18(25-11-4-5-13-10(7-11)8-15(29)26-13)28-16(12)27-14-3-1-2-6-23-17(14)30/h4-5,7,9,14H,1-3,6,8H2,(H,23,30)(H,26,29)(H2,24,25,27,28)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged FAK (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylation				Bioorg Med Chem Lett 18: 6071-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.030 BindingDB Entry DOI: 10.7270/Q2C8295H
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