Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Focal adhesion kinase 1' and Ligand = 'BDBM50246284'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50246284 (CHEMBL487057 | N4-((1R,2R)-2-Dimethylamino-cyclope...) Show SMILES CN(C)[C@@H]1CCC[C@H]1Nc1nc(Nc2ccc3c(CN(C)S3(=O)=O)c2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N6O2S/c1-28(2)16-6-4-5-15(16)26-18-14(20(21,22)23)10-24-19(27-18)25-13-7-8-17-12(9-13)11-29(3)32(17,30)31/h7-10,15-16H,4-6,11H2,1-3H3,(H2,24,25,26,27)/t15-,16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged FAK (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylation				Bioorg Med Chem Lett 18: 6071-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.030 BindingDB Entry DOI: 10.7270/Q2C8295H
					More data for this Ligand-Target Pair