Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Focal adhesion kinase 1' and Ligand = 'BDBM50430290'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50430290 (CHEMBL2333443) Show SMILES CN1c2ccc(NCc3ccc(Br)cc3)cc2-c2c(cnn2C)S1(=O)=O Show InChI InChI=1S/C18H17BrN4O2S/c1-22-18-15-9-14(20-10-12-3-5-13(19)6-4-12)7-8-16(15)23(2)26(24,25)17(18)11-21-22/h3-9,11,20H,10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assay				Bioorg Med Chem Lett 23: 1779-85 (2013) Article DOI: 10.1016/j.bmcl.2013.01.047 BindingDB Entry DOI: 10.7270/Q26Q1ZK9
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50430290 (CHEMBL2333443) Show SMILES CN1c2ccc(NCc3ccc(Br)cc3)cc2-c2c(cnn2C)S1(=O)=O Show InChI InChI=1S/C18H17BrN4O2S/c1-22-18-15-9-14(20-10-12-3-5-13(19)6-4-12)7-8-16(15)23(2)26(24,25)17(18)11-21-22/h3-9,11,20H,10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of intracellular FAK autophosphorylation in human PC3 M-luc cells after 2 hrs				Bioorg Med Chem Lett 23: 1779-85 (2013) Article DOI: 10.1016/j.bmcl.2013.01.047 BindingDB Entry DOI: 10.7270/Q26Q1ZK9
					More data for this Ligand-Target Pair