Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50030474 (Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a |
Suez Canal University Curated by ChEMBL | Assay Description Agonist activity at FFAR1 (unknown origin) assessed as increase in ERK1/2 MAP kinase phosphorylation | Bioorg Med Chem Lett 24: 5330-6 (2014) Article DOI: 10.1016/j.bmcl.2014.07.043 BindingDB Entry DOI: 10.7270/Q2PR7XM9 | |||||||||||
More data for this Ligand-Target Pair |