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Found 1 hit Enz. Inhib. hit(s) with Target = 'G protein-activated inward rectifier potassium channel 4' and Ligand = 'BDBM50202477'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G protein-activated inward rectifier potassium channel 4


(Homo sapiens (Human))		BDBM50202477
PNG
(CHEMBL3955249)
Show SMILES [H][C@]12[C@@H](OC(=O)c3ccccc3)[C@@H](C)C[C@]1(OC(C)=O)[C@@H](OC(C)=O)[C@]1(C)OC[C@@]3([C@@H]2OC(C)=O)C(=O)C=C[C@@H]([C@@]13[H])C(C)(C)OC(C)=O |r,c:40|
Show InChI InChI=1S/C35H42O12/c1-18-16-35(47-22(5)39)26(27(18)45-30(41)23-12-10-9-11-13-23)29(43-19(2)36)34-17-42-33(8,31(35)44-20(3)37)28(34)24(14-15-25(34)40)32(6,7)46-21(4)38/h9-15,18,24,26-29,31H,16-17H2,1-8H3/t18-,24-,26+,27-,28-,29+,31-,33+,34+,35+/m0/s1
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Similars
Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



Rytmion Ltd.

Curated by ChEMBL


Assay Description
Inhibition of GTPgammaS-induced activation of GIRK1/4 (unknown origin) expressed in HEK293 cells assessed as decrease in channel current after 2 mins...

J Nat Prod 79: 1990-2004 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00260
BindingDB Entry DOI: 10.7270/Q2CC12NJ
More data for this
Ligand-Target Pair