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Found 1 hit Enz. Inhib. hit(s) with Target = 'G protein-activated inward rectifier potassium channel 4' and Ligand = 'BDBM50202477'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-activated inward rectifier potassium channel 4


(Homo sapiens (Human))
BDBM50202477
PNG
(CHEMBL3955249)
Show SMILES [H][C@]12[C@@H](OC(=O)c3ccccc3)[C@@H](C)C[C@]1(OC(C)=O)[C@@H](OC(C)=O)[C@]1(C)OC[C@@]3([C@@H]2OC(C)=O)C(=O)C=C[C@@H]([C@@]13[H])C(C)(C)OC(C)=O |r,c:40|
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



Rytmion Ltd.

Curated by ChEMBL


Assay Description
Inhibition of GTPgammaS-induced activation of GIRK1/4 (unknown origin) expressed in HEK293 cells assessed as decrease in channel current after 2 mins...


J Nat Prod 79: 1990-2004 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00260
More data for this
Ligand-Target Pair