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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'G protein-coupled receptor 44' and Ligand = 'BDBM124825'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM124825
PNG
(US8759386, 22)
Show SMILES CCc1nn(Cc2ccc(NC(=O)c3cc4ccccc4n3CC)cc2)c(CC)c1CC(O)=O
Show InChI InChI=1S/C27H30N4O3/c1-4-22-21(16-26(32)33)23(5-2)31(29-22)17-18-11-13-20(14-12-18)28-27(34)25-15-19-9-7-8-10-24(19)30(25)6-3/h7-15H,4-6,16-17H2,1-3H3,(H,28,34)(H,32,33)
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PC cid
PC sid
UniChem
US Patent
0.200 -55.4n/an/an/an/an/a7.425



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...


US Patent US8759386 (2014)

More data for this
Ligand-Target Pair