Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'G protein-coupled receptor kinase 5' and Ligand = 'BDBM50173316'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor kinase 5 (Homo sapiens (Human))	BDBM50173316 (CHEMBL3810250) Show SMILES CC1=C(C(NC(=O)N1)c1ccc(F)c(c1)C(O)=O)C(=O)Nc1ccc2[nH]ncc2c1 |t:1| Show InChI InChI=1S/C20H16FN5O4/c1-9-16(18(27)24-12-3-5-15-11(6-12)8-22-26-15)17(25-20(30)23-9)10-2-4-14(21)13(7-10)19(28)29/h2-8,17H,1H3,(H,22,26)(H,24,27)(H,28,29)(H2,23,25,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Temple University Curated by ChEMBL					Assay Description Inhibition of GRK5 (unknown origin) using tubulin as substrate by SDS-PAGE method				J Med Chem 59: 3793-807 (2016) Article DOI: 10.1021/acs.jmedchem.5b02000 BindingDB Entry DOI: 10.7270/Q2JQ12X4
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