Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G-protein coupled bile acid receptor 1 (Homo sapiens (Human)) | BDBM19190 ((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
Zydus Research Centre Curated by ChEMBL | Assay Description Agonist activity at TGR5 in human whole blood assessed as inhibition of LPS-induced TNF-alpha release | ACS Med Chem Lett 7: 51-5 (2016) Article DOI: 10.1021/acsmedchemlett.5b00323 BindingDB Entry DOI: 10.7270/Q2125VJ1 | |||||||||||
More data for this Ligand-Target Pair |