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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 35' and Ligand = 'BDBM50436033'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 35


(Homo sapiens (Human))
BDBM50436033
PNG
(CHEMBL2392150)
Show SMILES OC(=O)c1cc(=O)c2cccc(NC(=O)Cc3ccccc3)c2o1
Show InChI InChI=1S/C18H13NO5/c20-14-10-15(18(22)23)24-17-12(14)7-4-8-13(17)19-16(21)9-11-5-2-1-3-6-11/h1-8,10H,9H2,(H,19,21)(H,22,23)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.72E+3n/an/an/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysis


J Med Chem 56: 7084-99 (2013)

Checked by Author
Article DOI: 10.1021/jm4009373
More data for this
Ligand-Target Pair
G-protein coupled receptor 35


(Homo sapiens (Human))
BDBM50436033
PNG
(CHEMBL2392150)
Show SMILES OC(=O)c1cc(=O)c2cccc(NC(=O)Cc3ccccc3)c2o1
Show InChI InChI=1S/C18H13NO5/c20-14-10-15(18(22)23)24-17-12(14)7-4-8-13(17)19-16(21)9-11-5-2-1-3-6-11/h1-8,10H,9H2,(H,19,21)(H,22,23)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 8.96E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...


J Med Chem 56: 5182-97 (2013)


Article DOI: 10.1021/jm400587g
More data for this
Ligand-Target Pair