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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'GPR24' and Ligand = 'BDBM50219058'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GPR24


(RAT)
BDBM50219058
PNG
(CHEMBL244004 | N-(3-{1-[4-(3,4-dimethylphenyl)-4-o...)
Show SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(C)c(C)c2)CC1
Show InChI InChI=1S/C25H32N2O2/c1-18-9-10-23(16-19(18)2)25(29)8-5-13-27-14-11-21(12-15-27)22-6-4-7-24(17-22)26-20(3)28/h4,6-7,9-10,16-17,21H,5,8,11-15H2,1-3H3,(H,26,28)
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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
100n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219058
PNG
(CHEMBL244004 | N-(3-{1-[4-(3,4-dimethylphenyl)-4-o...)
Show SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(C)c(C)c2)CC1
Show InChI InChI=1S/C25H32N2O2/c1-18-9-10-23(16-19(18)2)25(29)8-5-13-27-14-11-21(12-15-27)22-6-4-7-24(17-22)26-20(3)28/h4,6-7,9-10,16-17,21H,5,8,11-15H2,1-3H3,(H,26,28)
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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at rat MCH1 receptor expressed in HEK293 cells by FLIPR calcium mobility assay


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair