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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'GTPase HRas' and Ligand = 'BDBM50287951'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
GTPase HRas


(Homo sapiens (Human))		BDBM50287951
PNG
(3-[(3aS,4R,6R,6aR)-6-(4-Chloro-6-methoxy-3-methyl-...)
Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@@H]1O[C@H](OC(O)CC(=O)c2ccccc2)[C@H]2OC(=S)O[C@@H]12
Show InChI InChI=1S/C26H22ClN3O7S/c1-12-19-20(27)15-10-14(33-2)8-9-16(15)28-23(19)30(29-12)24-21-22(36-26(38)35-21)25(37-24)34-18(32)11-17(31)13-6-4-3-5-7-13/h3-10,18,21-22,24-25,32H,11H2,1-2H3/t18?,21-,22+,24-,25+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
n/an/a 1.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of nucleotide exchange process of oncogenic Ras in vitro

Bioorg Med Chem Lett 6: 195-200 (1996)


Article DOI: 10.1016/0960-894X(95)00574-D
BindingDB Entry DOI: 10.7270/Q2G160TB
More data for this
Ligand-Target Pair