Found 3 hits Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid type B receptor subunit 1' and Ligand = 'BDBM24183' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Gamma-aminobutyric acid type B receptor subunit 1
(Rattus norvegicus (Rat)) | BDBM24183
(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) | PDB
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sydney
Curated by PDSP Ki Database
| |
Eur J Pharmacol 329: 223-9 (1997)
BindingDB Entry DOI: 10.7270/Q2H41PZV |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Gamma-aminobutyric acid type B receptor subunit 1
(Rattus norvegicus (Rat)) | BDBM24183
(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
J Neurochem 32: 713-8 (1979)
Article DOI: 10.1111/j.1471-4159.1979.tb04553.x BindingDB Entry DOI: 10.7270/Q29W0D0B |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Gamma-aminobutyric acid type B receptor subunit 1
(Homo sapiens (Human)) | BDBM24183
(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
University of Sydney
Curated by ChEMBL
| Assay Description Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m... |
J Med Chem 51: 3825-40 (2008)
Article DOI: 10.1021/jm7015842 BindingDB Entry DOI: 10.7270/Q27M07RR |
More data for this Ligand-Target Pair | 3D Structure (crystal) |