BindingDB PrimarySearch

Found 7 hits Enz. Inhib. hit(s) with Target = 'Gamma-butyrobetaine dioxygenase' and Ligand = 'BDBM50028969'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human))	BDBM50028969 (CHEMBL3122204) Show SMILES [Se]([Se]c1ccccc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of human BBOX pre-incubated for 25 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay				Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human))	BDBM50028969 (CHEMBL3122204) Show SMILES [Se]([Se]c1ccccc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of human BBOX pre-incubated for 20 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay				Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human))	BDBM50028969 (CHEMBL3122204) Show SMILES [Se]([Se]c1ccccc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of human BBOX pre-incubated for 10 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay				Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human))	BDBM50028969 (CHEMBL3122204) Show SMILES [Se]([Se]c1ccccc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of human BBOX pre-incubated for 15 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay				Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human))	BDBM50028969 (CHEMBL3122204) Show SMILES [Se]([Se]c1ccccc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of human BBOX pre-incubated for 1 min using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay				Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human))	BDBM50028969 (CHEMBL3122204) Show SMILES [Se]([Se]c1ccccc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Binding affinity to human BBOX in presence of Fe(II) by tryptophan fluorescence quenching binding assay				Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human))	BDBM50028969 (CHEMBL3122204) Show SMILES [Se]([Se]c1ccccc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Binding affinity to human BBOX by tryptophan fluorescence quenching binding assay				Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair