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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT)' and Ligand = 'BDBM50134310'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT)


(Homo sapiens (Human))
BDBM50134310
PNG
(9-Methoxy-2-methyl-2,3,10,10a-tetrahydro-pyrazino[...)
Show SMILES COc1cccc2N3C(Cc12)C(=O)N(C)CC3=O
Show InChI InChI=1S/C13H14N2O3/c1-14-7-12(16)15-9-4-3-5-11(18-2)8(9)6-10(15)13(14)17/h3-5,10H,6-7H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Imperial College of Science

Curated by ChEMBL


Assay Description
Inhibition of [3H]-GGPP incorporation into recombinant human Ha-Ras-CVLL by Geranylgeranyl transferase type I


Bioorg Med Chem Lett 13: 3661-3 (2003)


BindingDB Entry DOI: 10.7270/Q2CF9PHX
More data for this
Ligand-Target Pair