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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT)' and Ligand = 'BDBM50134311'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT)


(Homo sapiens (Human))
BDBM50134311
PNG
(3-Benzyldisulfanyl-9-methoxy-2-methyl-2,3-dihydro-...)
Show SMILES COc1cccc2n3c(cc12)C(=O)N(C)C(SSCc1ccccc1)C3=O
Show InChI InChI=1S/C20H18N2O3S2/c1-21-18(23)16-11-14-15(9-6-10-17(14)25-2)22(16)19(24)20(21)27-26-12-13-7-4-3-5-8-13/h3-11,20H,12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
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antibodypedia
GoogleScholar
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CHEMBL
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Imperial College of Science

Curated by ChEMBL


Assay Description
Inhibition of [3H]-GGPP incorporation into recombinant human Ha-Ras-CVLL by Geranylgeranyl transferase type I


Bioorg Med Chem Lett 13: 3661-3 (2003)


BindingDB Entry DOI: 10.7270/Q2CF9PHX
More data for this
Ligand-Target Pair