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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ghrelin receptor' and Ligand = 'BDBM50222871'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ghrelin receptor


(Ovis aries)
BDBM50222871
PNG
(7-(4-chlorophenyl)-3-[(1-ethylpiperidin-3-yl)methy...)
Show SMILES CCN1CCCC(Cn2c(nc3cc(ccc3c2=O)-c2ccc(Cl)cc2)-c2ccccc2OC)C1 |w:6.6|
Show InChI InChI=1S/C29H30ClN3O2/c1-3-32-16-6-7-20(18-32)19-33-28(25-8-4-5-9-27(25)35-2)31-26-17-22(12-15-24(26)29(33)34)21-10-13-23(30)14-11-21/h4-5,8-15,17,20H,3,6-7,16,18-19H2,1-2H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bayer Pharmaceuticals Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay


J Med Chem 50: 5202-16 (2007)


Article DOI: 10.1021/jm070071+
BindingDB Entry DOI: 10.7270/Q2WH2QT2
More data for this
Ligand-Target Pair