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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ghrelin receptor' and Ligand = 'BDBM50222880'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ghrelin receptor


(Ovis aries)
BDBM50222880
PNG
(6-(2-chlorophenyl)-2-isopropyl-3-(((R)-1-isopropyl...)
Show SMILES CC(C)N1CCC[C@@H](Cn2c(nc3ccc(cc3c2=O)-c2ccccc2Cl)C(C)C)C1
Show InChI InChI=1S/C26H32ClN3O/c1-17(2)25-28-24-12-11-20(21-9-5-6-10-23(21)27)14-22(24)26(31)30(25)16-19-8-7-13-29(15-19)18(3)4/h5-6,9-12,14,17-19H,7-8,13,15-16H2,1-4H3/t19-/m1/s1
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.80E+3n/an/an/an/an/an/an/an/a



Bayer Pharmaceuticals Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay


J Med Chem 50: 5202-16 (2007)


Article DOI: 10.1021/jm070071+
BindingDB Entry DOI: 10.7270/Q2WH2QT2
More data for this
Ligand-Target Pair