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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ghrelin receptor' and Ligand = 'BDBM50222887'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ghrelin receptor


(Ovis aries)
BDBM50222887
PNG
((S)-6-(4-chlorophenyl)-3-((1-ethylpiperidin-3-yl)m...)
Show SMILES CCN1CCC[C@H](Cn2c(nc3ccc(cc3c2=O)-c2ccc(Cl)cc2)-c2ccc(cc2)C(F)(F)F)C1
Show InChI InChI=1S/C29H27ClF3N3O/c1-2-35-15-3-4-19(17-35)18-36-27(21-5-10-23(11-6-21)29(31,32)33)34-26-14-9-22(16-25(26)28(36)37)20-7-12-24(30)13-8-20/h5-14,16,19H,2-4,15,17-18H2,1H3/t19-/m0/s1
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
16n/an/an/an/an/an/an/an/a



Bayer Pharmaceuticals Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay


J Med Chem 50: 5202-16 (2007)


Article DOI: 10.1021/jm070071+
BindingDB Entry DOI: 10.7270/Q2WH2QT2
More data for this
Ligand-Target Pair