Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50007243'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50007243 (CHEMBL3238231) Show SMILES C[C@H]1CC[C@]2(CC1)N=C(C(=O)N2[C@H](CCC(C)(C)C)c1ccc(cc1)C(=O)NCc1nn[nH]n1)c1cc(Cl)cc(Cl)c1 |r,wU:12.14,1.0,wD:4.3,c:8,(1.27,-23.79,;2.61,-23.02,;2.87,-21.51,;4.32,-20.98,;5.5,-21.96,;5.24,-23.48,;3.79,-24.01,;5.92,-20.48,;7.46,-20.42,;8,-21.87,;9.47,-22.29,;6.78,-22.82,;6.84,-24.36,;5.51,-25.14,;5.53,-26.68,;4.21,-27.47,;4.23,-29.01,;2.86,-26.71,;2.87,-28.22,;8.16,-25.14,;8.14,-26.69,;9.47,-27.47,;10.81,-26.72,;10.83,-25.18,;9.51,-24.4,;12.14,-27.51,;12.12,-29.05,;13.47,-26.76,;14.8,-27.54,;16.14,-26.79,;17.54,-27.42,;18.58,-26.29,;17.83,-24.95,;16.32,-25.25,;8.24,-19.09,;7.48,-17.76,;8.25,-16.43,;7.49,-15.09,;9.8,-16.43,;10.56,-17.77,;12.1,-17.78,;9.78,-19.11,)| Show InChI InChI=1S/C31H37Cl2N7O2/c1-19-9-13-31(14-10-19)35-27(22-15-23(32)17-24(33)16-22)29(42)40(31)25(11-12-30(2,3)4)20-5-7-21(8-6-20)28(41)34-18-26-36-38-39-37-26/h5-8,15-17,19,25H,9-14,18H2,1-4H3,(H,34,41)(H,36,37,38,39)/t19-,25-,31-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from recombinant human GCGR expressed in CHO cells after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50007243 (CHEMBL3238231) Show SMILES C[C@H]1CC[C@]2(CC1)N=C(C(=O)N2[C@H](CCC(C)(C)C)c1ccc(cc1)C(=O)NCc1nn[nH]n1)c1cc(Cl)cc(Cl)c1 |r,wU:12.14,1.0,wD:4.3,c:8,(1.27,-23.79,;2.61,-23.02,;2.87,-21.51,;4.32,-20.98,;5.5,-21.96,;5.24,-23.48,;3.79,-24.01,;5.92,-20.48,;7.46,-20.42,;8,-21.87,;9.47,-22.29,;6.78,-22.82,;6.84,-24.36,;5.51,-25.14,;5.53,-26.68,;4.21,-27.47,;4.23,-29.01,;2.86,-26.71,;2.87,-28.22,;8.16,-25.14,;8.14,-26.69,;9.47,-27.47,;10.81,-26.72,;10.83,-25.18,;9.51,-24.4,;12.14,-27.51,;12.12,-29.05,;13.47,-26.76,;14.8,-27.54,;16.14,-26.79,;17.54,-27.42,;18.58,-26.29,;17.83,-24.95,;16.32,-25.25,;8.24,-19.09,;7.48,-17.76,;8.25,-16.43,;7.49,-15.09,;9.8,-16.43,;10.56,-17.77,;12.1,-17.78,;9.78,-19.11,)| Show InChI InChI=1S/C31H37Cl2N7O2/c1-19-9-13-31(14-10-19)35-27(22-15-23(32)17-24(33)16-22)29(42)40(31)25(11-12-30(2,3)4)20-5-7-21(8-6-20)28(41)34-18-26-36-38-39-37-26/h5-8,15-17,19,25H,9-14,18H2,1-4H3,(H,34,41)(H,36,37,38,39)/t19-,25-,31-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-stimulated cAMP production preincubated for 30 mins follo...				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair