Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50120333'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50120333 (CHEMBL3616681) Show SMILES CC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(Cl)cc(c2)C(F)(F)F)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C33H24ClF6N3O4/c1-18(19-2-4-21(5-3-19)31(46)41-13-12-29(44)45)43-28-16-22(20-6-9-26(10-7-20)47-33(38,39)40)8-11-27(28)30(42-43)23-14-24(32(35,36)37)17-25(34)15-23/h2-11,14-18H,12-13H2,1H3,(H,41,46)(H,44,45)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120333 (CHEMBL3616681) Show SMILES CC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(Cl)cc(c2)C(F)(F)F)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C33H24ClF6N3O4/c1-18(19-2-4-21(5-3-19)31(46)41-13-12-29(44)45)43-28-16-22(20-6-9-26(10-7-20)47-33(38,39)40)8-11-27(28)30(42-43)23-14-24(32(35,36)37)17-25(34)15-23/h2-11,14-18H,12-13H2,1H3,(H,41,46)(H,44,45)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human glucagon receptor expressed in CHO cells assessed as reduction in glucagon-induced cAMP production				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair