Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50014539'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50014539 (CHEMBL3261412) Show SMILES C[C@@H](CNc1cccc2n(ncc12)-c1cccnc1)NS(=O)(=O)c1c(C)cc(C)cc1C |r| Show InChI InChI=1S/C24H27N5O2S/c1-16-11-17(2)24(18(3)12-16)32(30,31)28-19(4)13-26-22-8-5-9-23-21(22)15-27-29(23)20-7-6-10-25-14-20/h5-12,14-15,19,26,28H,13H2,1-4H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human PBMC assessed as inhibition of LPS-stimulated TNF-alpha release				Bioorg Med Chem Lett 24: 2571-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.070 BindingDB Entry DOI: 10.7270/Q2JQ12J6
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50014539 (CHEMBL3261412) Show SMILES C[C@@H](CNc1cccc2n(ncc12)-c1cccnc1)NS(=O)(=O)c1c(C)cc(C)cc1C |r| Show InChI InChI=1S/C24H27N5O2S/c1-16-11-17(2)24(18(3)12-16)32(30,31)28-19(4)13-26-22-8-5-9-23-21(22)15-27-29(23)20-7-6-10-25-14-20/h5-12,14-15,19,26,28H,13H2,1-4H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human Chago K1 cells assessed as gene transrepression by Lac-Z reporter gene assay				Bioorg Med Chem Lett 24: 2571-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.070 BindingDB Entry DOI: 10.7270/Q2JQ12J6
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50014539 (CHEMBL3261412) Show SMILES C[C@@H](CNc1cccc2n(ncc12)-c1cccnc1)NS(=O)(=O)c1c(C)cc(C)cc1C |r| Show InChI InChI=1S/C24H27N5O2S/c1-16-11-17(2)24(18(3)12-16)32(30,31)28-19(4)13-26-22-8-5-9-23-21(22)15-27-29(23)20-7-6-10-25-14-20/h5-12,14-15,19,26,28H,13H2,1-4H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polarization assay				Bioorg Med Chem Lett 24: 2571-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.070 BindingDB Entry DOI: 10.7270/Q2JQ12J6
					More data for this Ligand-Target Pair