Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50091045'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50091045 (CHEMBL3582113) Show SMILES Cc1noc(C)c1-c1cc2c(NC(C)(C)C(=O)C2(C)C)c2CCCCc12 |(2.38,-4.74,;3.3,-3.91,;4.82,-4.24,;5.6,-2.89,;4.56,-1.74,;4.81,-.52,;3.16,-2.38,;1.81,-1.6,;.47,-2.38,;-.85,-1.6,;-.85,,;-2.21,.72,;-3.55,,;-4.62,-.63,;-3.5,1.24,;-3.55,-1.6,;-4.63,-2.23,;-2.21,-2.38,;-1.12,-2.98,;-3.3,-2.97,;.47,.72,;.47,2.27,;1.81,3.06,;3.17,2.27,;3.17,.72,;1.81,,)| Show InChI InChI=1S/C22H28N2O2/c1-12-18(13(2)26-24-12)16-11-17-19(15-10-8-7-9-14(15)16)23-22(5,6)20(25)21(17,3)4/h11,23H,7-10H2,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	106	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-dexamethasone from cytosolic fraction of human recombinant glucocorticoid receptor by scintillation counting analysis				J Med Chem 58: 4918-26 (2015) Article DOI: 10.1021/jm501758q BindingDB Entry DOI: 10.7270/Q2WM1G4V
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50091045 (CHEMBL3582113) Show SMILES Cc1noc(C)c1-c1cc2c(NC(C)(C)C(=O)C2(C)C)c2CCCCc12 |(2.38,-4.74,;3.3,-3.91,;4.82,-4.24,;5.6,-2.89,;4.56,-1.74,;4.81,-.52,;3.16,-2.38,;1.81,-1.6,;.47,-2.38,;-.85,-1.6,;-.85,,;-2.21,.72,;-3.55,,;-4.62,-.63,;-3.5,1.24,;-3.55,-1.6,;-4.63,-2.23,;-2.21,-2.38,;-1.12,-2.98,;-3.3,-2.97,;.47,.72,;.47,2.27,;1.81,3.06,;3.17,2.27,;3.17,.72,;1.81,,)| Show InChI InChI=1S/C22H28N2O2/c1-12-18(13(2)26-24-12)16-11-17-19(15-10-8-7-9-14(15)16)23-22(5,6)20(25)21(17,3)4/h11,23H,7-10H2,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor transfected in CHOK1 cells assessed as inhibition of dexamethasone-induced receptor transcriptio...				J Med Chem 58: 4918-26 (2015) Article DOI: 10.1021/jm501758q BindingDB Entry DOI: 10.7270/Q2WM1G4V
					More data for this Ligand-Target Pair