Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50103247'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103247 (10-Methoxy-2,2,4-trimethyl-5-(3-trifluoromethyl-ph...) Show SMILES COc1cccc2OC(c3cccc(c3)C(F)(F)F)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:29| Show InChI InChI=1S/C27H24F3NO2/c1-15-14-26(2,3)31-19-12-11-18-23-20(32-4)9-6-10-21(23)33-25(24(18)22(15)19)16-7-5-8-17(13-16)27(28,29)30/h5-14,25,31H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for glucocorticoid receptor				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103247 (10-Methoxy-2,2,4-trimethyl-5-(3-trifluoromethyl-ph...) Show SMILES COc1cccc2OC(c3cccc(c3)C(F)(F)F)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:29| Show InChI InChI=1S/C27H24F3NO2/c1-15-14-26(2,3)31-19-12-11-18-23-20(32-4)9-6-10-21(23)33-25(24(18)22(15)19)16-7-5-8-17(13-16)27(28,29)30/h5-14,25,31H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Repression activity of GR ligand with interleukin-6 receptor in native cell assay using dexamethasone was determined as maximal potency				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103247 (10-Methoxy-2,2,4-trimethyl-5-(3-trifluoromethyl-ph...) Show SMILES COc1cccc2OC(c3cccc(c3)C(F)(F)F)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:29| Show InChI InChI=1S/C27H24F3NO2/c1-15-14-26(2,3)31-19-12-11-18-23-20(32-4)9-6-10-21(23)33-25(24(18)22(15)19)16-7-5-8-17(13-16)27(28,29)30/h5-14,25,31H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing glucocorticoid receptor				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103247 (10-Methoxy-2,2,4-trimethyl-5-(3-trifluoromethyl-ph...) Show SMILES COc1cccc2OC(c3cccc(c3)C(F)(F)F)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:29| Show InChI InChI=1S/C27H24F3NO2/c1-15-14-26(2,3)31-19-12-11-18-23-20(32-4)9-6-10-21(23)33-25(24(18)22(15)19)16-7-5-8-17(13-16)27(28,29)30/h5-14,25,31H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Transcriptional repression activity in HEP G2 cells expressing glucocorticoid receptor compared to dexamethasone				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103247 (10-Methoxy-2,2,4-trimethyl-5-(3-trifluoromethyl-ph...) Show SMILES COc1cccc2OC(c3cccc(c3)C(F)(F)F)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:29| Show InChI InChI=1S/C27H24F3NO2/c1-15-14-26(2,3)31-19-12-11-18-23-20(32-4)9-6-10-21(23)33-25(24(18)22(15)19)16-7-5-8-17(13-16)27(28,29)30/h5-14,25,31H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Glucocorticoid-induced aromatase activity in human skin fibroblasts				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair