Compile Data Set for Download or QSAR

Found 8 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50103251'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103251 (5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...) Show SMILES COc1cccc2OC(c3cc(Cl)cc(Cl)c3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:27| Show InChI InChI=1S/C26H23Cl2NO2/c1-14-13-26(2,3)29-19-9-8-18-23-20(30-4)6-5-7-21(23)31-25(24(18)22(14)19)15-10-16(27)12-17(28)11-15/h5-13,25,29H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for glucocorticoid receptor				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103251 (5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...) Show SMILES COc1cccc2OC(c3cc(Cl)cc(Cl)c3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:27| Show InChI InChI=1S/C26H23Cl2NO2/c1-14-13-26(2,3)29-19-9-8-18-23-20(30-4)6-5-7-21(23)31-25(24(18)22(14)19)15-10-16(27)12-17(28)11-15/h5-13,25,29H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for glucocorticoid receptor				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103251 (5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...) Show SMILES COc1cccc2OC(c3cc(Cl)cc(Cl)c3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:27| Show InChI InChI=1S/C26H23Cl2NO2/c1-14-13-26(2,3)29-19-9-8-18-23-20(30-4)6-5-7-21(23)31-25(24(18)22(14)19)15-10-16(27)12-17(28)11-15/h5-13,25,29H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for glucocorticoid receptor				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103251 (5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...) Show SMILES COc1cccc2OC(c3cc(Cl)cc(Cl)c3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:27| Show InChI InChI=1S/C26H23Cl2NO2/c1-14-13-26(2,3)29-19-9-8-18-23-20(30-4)6-5-7-21(23)31-25(24(18)22(14)19)15-10-16(27)12-17(28)11-15/h5-13,25,29H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Transcriptional repression of IL-1 stimulated IL-6 expression in native cells compared to dexamethasone				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103251 (5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...) Show SMILES COc1cccc2OC(c3cc(Cl)cc(Cl)c3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:27| Show InChI InChI=1S/C26H23Cl2NO2/c1-14-13-26(2,3)29-19-9-8-18-23-20(30-4)6-5-7-21(23)31-25(24(18)22(14)19)15-10-16(27)12-17(28)11-15/h5-13,25,29H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Repression activity of GR ligand with interleukin-6 receptor in native cell assay using dexamethasone was determined as maximal potency				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103251 (5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...) Show SMILES COc1cccc2OC(c3cc(Cl)cc(Cl)c3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:27| Show InChI InChI=1S/C26H23Cl2NO2/c1-14-13-26(2,3)29-19-9-8-18-23-20(30-4)6-5-7-21(23)31-25(24(18)22(14)19)15-10-16(27)12-17(28)11-15/h5-13,25,29H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Transcriptional repression activity in HEP G2 cells expressing glucocorticoid receptor compared to dexamethasone				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103251 (5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...) Show SMILES COc1cccc2OC(c3cc(Cl)cc(Cl)c3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:27| Show InChI InChI=1S/C26H23Cl2NO2/c1-14-13-26(2,3)29-19-9-8-18-23-20(30-4)6-5-7-21(23)31-25(24(18)22(14)19)15-10-16(27)12-17(28)11-15/h5-13,25,29H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing glucocorticoid receptor				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50103251 (5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...) Show SMILES COc1cccc2OC(c3cc(Cl)cc(Cl)c3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:27| Show InChI InChI=1S/C26H23Cl2NO2/c1-14-13-26(2,3)29-19-9-8-18-23-20(30-4)6-5-7-21(23)31-25(24(18)22(14)19)15-10-16(27)12-17(28)11-15/h5-13,25,29H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	139	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Glucocorticoid-induced aromatase activity in human skin fibroblasts				J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP
					More data for this Ligand-Target Pair