Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50103254 (CHEMBL317578 | Dimethyl-carbamic acid 3-(10-methox...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]- dexamethasone from glucocorticoid receptor | J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50103254 (CHEMBL317578 | Dimethyl-carbamic acid 3-(10-methox...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Transcriptional repression activity in HEP G2 cells expressing glucocorticoid receptor compared to dexamethasone | J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50103254 (CHEMBL317578 | Dimethyl-carbamic acid 3-(10-methox...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Transcriptional activation in CV-1 cells expressing glucocorticoid receptor | J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50103254 (CHEMBL317578 | Dimethyl-carbamic acid 3-(10-methox...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Repression activity of GR ligand with interleukin-6 receptor in native cell assay using dexamethasone was determined as maximal potency | J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50103254 (CHEMBL317578 | Dimethyl-carbamic acid 3-(10-methox...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 216 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Glucocorticoid-induced aromatase activity in human skin fibroblasts | J Med Chem 44: 2879-85 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6RJP | |||||||||||
More data for this Ligand-Target Pair |