Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50107350'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50107350 (5-Benzyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...) Show SMILES COc1cccc2OC(C3CCCC3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:24| Show InChI InChI=1S/C25H29NO2/c1-15-14-25(2,3)26-18-13-12-17-22-19(27-4)10-7-11-20(22)28-24(23(17)21(15)18)16-8-5-6-9-16/h7,10-14,16,24,26H,5-6,8-9H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucocorticoid receptor (GR) by displacing [3H]-Dexamethasone				J Med Chem 44: 4481-91 (2001) BindingDB Entry DOI: 10.7270/Q2CZ36F4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50107350 (5-Benzyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...) Show SMILES COc1cccc2OC(C3CCCC3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:24| Show InChI InChI=1S/C25H29NO2/c1-15-14-25(2,3)26-18-13-12-17-22-19(27-4)10-7-11-20(22)28-24(23(17)21(15)18)16-8-5-6-9-16/h7,10-14,16,24,26H,5-6,8-9H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).				J Med Chem 44: 4481-91 (2001) BindingDB Entry DOI: 10.7270/Q2CZ36F4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50107350 (5-Benzyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...) Show SMILES COc1cccc2OC(C3CCCC3)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:24| Show InChI InChI=1S/C25H29NO2/c1-15-14-25(2,3)26-18-13-12-17-22-19(27-4)10-7-11-20(22)28-24(23(17)21(15)18)16-8-5-6-9-16/h7,10-14,16,24,26H,5-6,8-9H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).				J Med Chem 44: 4481-91 (2001) BindingDB Entry DOI: 10.7270/Q2CZ36F4
					More data for this Ligand-Target Pair