new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50124621'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124621
PNG
(5-Allyl-10-methoxy-2,2,4,7-tetramethyl-2,5-dihydro...)
Show SMILES COc1ccc(C)c2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C24H27NO2/c1-7-8-19-21-16(22-18(26-6)12-9-14(2)23(22)27-19)10-11-17-20(21)15(3)13-24(4,5)25-17/h7,9-13,19,25H,1,8H2,2-6H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
2n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124621
PNG
(5-Allyl-10-methoxy-2,2,4,7-tetramethyl-2,5-dihydro...)
Show SMILES COc1ccc(C)c2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C24H27NO2/c1-7-8-19-21-16(22-18(26-6)12-9-14(2)23(22)27-19)10-11-17-20(21)15(3)13-24(4,5)25-17/h7,9-13,19,25H,1,8H2,2-6H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 81n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of dihydrofolate reductase DHFR in Pneumocystis carinii.


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair