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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50206946'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50206946
PNG
(CHEMBL3954977)
Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@H](O)[C@]1([H])c3ccc(cc3CC[C@@]21[H])C(=O)Nc1ncccc1C |r|
Show InChI InChI=1S/C28H32N2O3/c1-4-12-28(33)13-11-22-21-10-7-18-15-19(26(32)30-25-17(2)6-5-14-29-25)8-9-20(18)24(21)23(31)16-27(22,28)3/h5-6,8-9,14-15,21-24,31,33H,7,10-11,13,16H2,1-3H3,(H,29,30,32)/t21-,22-,23-,24+,27-,28-/m0/s1
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Similars
Article
PubMed
n/an/an/an/a 280n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at GR in human HepG2 cells assessed as protein mediated-transcriptional activity by MMTV-promoter driven luciferase reporter gene as...

Bioorg Med Chem Lett 27: 347-353 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.007
BindingDB Entry DOI: 10.7270/Q24B339Q
More data for this
Ligand-Target Pair