Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50355725'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355725 (CHEMBL1911282) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccc(C(=O)N2CCC(F)(F)C2)c(Cl)c1)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C29H24ClF2N5O3S/c1-28(2,26(39)35-27-36-33-15-41-27)23-18-5-3-4-6-22(18)40-24-19(23)9-10-21(34-24)16-7-8-17(20(30)13-16)25(38)37-12-11-29(31,32)14-37/h3-10,13,15,23H,11-12,14H2,1-2H3,(H,35,36,39)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.08	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of GS-red from glucocorticoid receptor by fluorescence polarization assay				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355725 (CHEMBL1911282) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccc(C(=O)N2CCC(F)(F)C2)c(Cl)c1)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C29H24ClF2N5O3S/c1-28(2,26(39)35-27-36-33-15-41-27)23-18-5-3-4-6-22(18)40-24-19(23)9-10-21(34-24)16-7-8-17(20(30)13-16)25(38)37-12-11-29(31,32)14-37/h3-10,13,15,23H,11-12,14H2,1-2H3,(H,35,36,39)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	33.8	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor alpha in IL-1beta-stimulated human A549 cells assessed as inhibition of NFkappaB-dependent E-sele...				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355725 (CHEMBL1911282) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccc(C(=O)N2CCC(F)(F)C2)c(Cl)c1)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C29H24ClF2N5O3S/c1-28(2,26(39)35-27-36-33-15-41-27)23-18-5-3-4-6-22(18)40-24-19(23)9-10-21(34-24)16-7-8-17(20(30)13-16)25(38)37-12-11-29(31,32)14-37/h3-10,13,15,23H,11-12,14H2,1-2H3,(H,35,36,39)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	329	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transactivation activity at glucocorticoid receptor alpha human 13D3/Huh7 cells assessed as induction of TAT activity after 4 hrs by spectrophotometr...				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355725 (CHEMBL1911282) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccc(C(=O)N2CCC(F)(F)C2)c(Cl)c1)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C29H24ClF2N5O3S/c1-28(2,26(39)35-27-36-33-15-41-27)23-18-5-3-4-6-22(18)40-24-19(23)9-10-21(34-24)16-7-8-17(20(30)13-16)25(38)37-12-11-29(31,32)14-37/h3-10,13,15,23H,11-12,14H2,1-2H3,(H,35,36,39)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transactivation activity at GR-alpha in human NP1 Hela cells assessed as inhibition of GAL4-DBD after 20 hrs by luciferase reporter gene assay				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355725 (CHEMBL1911282) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccc(C(=O)N2CCC(F)(F)C2)c(Cl)c1)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C29H24ClF2N5O3S/c1-28(2,26(39)35-27-36-33-15-41-27)23-18-5-3-4-6-22(18)40-24-19(23)9-10-21(34-24)16-7-8-17(20(30)13-16)25(38)37-12-11-29(31,32)14-37/h3-10,13,15,23H,11-12,14H2,1-2H3,(H,35,36,39)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	165	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transactivation activity at GR-alpha in human NP1 Hela cells assessed as induction of GAL4-DBD after 20 hrs by luciferase reporter gene assay				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50355725 (CHEMBL1911282) Show SMILES CC(C)([C@H]1c2ccccc2Oc2nc(ccc12)-c1ccc(C(=O)N2CCC(F)(F)C2)c(Cl)c1)C(=O)Nc1nncs1 |r| Show InChI InChI=1S/C29H24ClF2N5O3S/c1-28(2,26(39)35-27-36-33-15-41-27)23-18-5-3-4-6-22(18)40-24-19(23)9-10-21(34-24)16-7-8-17(20(30)13-16)25(38)37-12-11-29(31,32)14-37/h3-10,13,15,23H,11-12,14H2,1-2H3,(H,35,36,39)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor alpha in phorbol myristate acetate-stimulated human A549 cells assessed as inhibition of AP1 resp...				J Med Chem 54: 7318-33 (2011) Article DOI: 10.1021/jm200879j BindingDB Entry DOI: 10.7270/Q2W0969M
					More data for this Ligand-Target Pair